Science Homework Help

• Consider the disease X-syndrome. There are two alleles in the population
  of 7500 individuals: the wild-type allele A and the mutation allele a
  that are believed to have frequencies 0.98 and 0.02, respectively.

a) If the population is in Hardy-Weinberg equilibrium, how many individuals would you expect to see with the disease if the disease was fully recessive?

b) If two carriers of the mutation had children, what proportion would be expected to have the recessive disease?

c) If you observe 300 individuals with the recessive disease, what would your updated estimate of the mutation allele frequency be?

d) If the population is in Hardy-Weinberg equilibrium, how many individuals would you expect to see with the disease if the disease was a fully dominant?