Science Homework Help

Azusa Pacific University Counter Signaling Biology Discussion

 

Imagine that you have engineered a set of genes, each encoding a protein with a pair of conflicting signal sequences that specify different compartments. If the genes were expressed in a cell, predict which signal would win out for the following combinations. Explain your reasoning.

  1. Signals for import into nucleus and import into ER.
  2. Signals for import into peroxisomes and import into ER.

for these two cases, I know that signals for ER works first.

but I don’t completely understand. I know that ER signal is at N-terminus and peroxisome is at C-terminus. and I don’t understand how it affects the answer. and also I don’t understand how signals for ER can work before fully synthesized while others can’t.