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Current research studies on Sepsis have mainly focused on the management of care including the detection and bedside treatment of Sepsis patients and patients with septic shock. However, very little research exists regarding the factors determining the development, outcomes, and progression of sepsis and septic shocks. The gaps in sepsis research include the utilization of precision medicine to determine effective therapies for specific patients and times, whether rapid diagnostic tests are effective and should be incorporated into clinical practice, and the specific information indicative of organ dysfunction in septic patients. Other gaps include research evidence on the determinants of long-term sepsis mortality and morbidity, and the antibiotic therapy combinations to be used in the treatment of sepsis and septic shock (Coopersmith et al., 2018).

These gaps in sepsis research provide an opportunity for conducting more translational research towards treating and effectively managing sepsis. Future researchers should therefore focus on studying the factors underlying the development and progression of sepsis and septic shocks, factors determining sepsis morbidity and mortality, the use of precision medicine for the treatment of sepsis and septic shock, and the effective antibiotic combinations for managing septic shock. Such studies will be instrumental in improving the care for Sepsis patients and the achievement of quality healthcare outcomes.