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Why Vesicles Are Not Delivering Their Contents to The Endosome Question

 

I’m working on a biology question and need an explanation to help me study.

You have identified a disease in which vesicles are not delivering their contents to the endosome. Which of the following might be the underlying cause?

Group of answer choices

A mutation that decreases Rab5-GAP activity.

A mutation that increases Rab1 activity.

A mutation that increases endosomal t-SNARE expression.

A mutation that decreases PI 3-kinase activity.